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Computational Neuroimaging of Brain Disorders

We integrate longitudinal assessments and time-series analyses to map neural signal measures to neurological and psychiatric symptoms that manifest over various timescales from moments to months. Using advanced machine learning (ML) techniques, such as dimensionality reduction, multivariate linear models and artificial intelligence (AI)-driven models, we conduct multimodal neuroimaging studies combined with longitudinal phenotyping, computational modelling and neuroinformatics to establish reproducible brain-behavior associations. We aim to develop methods to identify neural circuit abnormalities underlying symptoms, develop multimodal neural markers of psychopathology, and inform symptom-specific pharmacological treatment strategies.

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Our Work

Discover how our lab contributes to open and inclusive human brain research.

Research

Projects

Focusing on the analysis of functional neuroimaging data (e.g. resting-state fMRI, EEG) and behavioral/clinical data, we develop quantitative approaches to test hypotheses on the neurobiological mechanisms underlying specific symptoms and cognitive impairments in psychiatric disorders such as schizophrenia.

  • Longitudinal Imaging of Schizophrenia in Adults (LISA)
  • Neural dynamics modelling
  • Brain states in fMRI and EEG
  • Open-source BrainCAP software development
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Projects
Publications
Papers

Publications

Check out our recent peer-reviewed journal articles.

  • Lee et al. (Biological Psychiatry 2025)
  • Lee et al. (PLoS Biology 2024)
  • Lee et al. (Neuroimage 2022)
  • Lee et al. (Neuroimage:Clinical 2018)
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Development

Software

We develop open-source software tools to analyze neuroimaging and behavioral measurements to help scientists conduct research with greater efficiency, reproducibility, and transparency.

  • BrainCAP (under development): https://github.com/Kangjoo/BrainCAP/tree/develop
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Software

Latest News

See what's new in the CNBD laboratory.

Opportunities for BME Undergraduates

Opportunities for BME Undergraduates

Mar. 16, 2026

We welcome undergraduate BME students to join our lab through the ARCH Program (Honors College) or the Coulter Undergraduate Research Excellence (CURE) Program for entry-level undergraduates.

Welcoming New Volunteers

Welcoming New Volunteers

Feb. 12, 2026

We are excited to welcome two new volunteers, Elysa Barrera and Diego Mora Ramos, to our team!

Open PhD positions

Open PhD positions

Dec. 10, 2025

The CNBD Lab is recruiting two PhD students to join us in Fall 2026. The priority deadline for internal fellowships is December 31, 2025, and the final application deadline is February 15, 2026.

Interested in working with us?

Join us based in the Department of Biomedical Engineering at Florida International University.

Email Dr. Lee BME PhD Program