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Computational Neuroimaging of Brain Disorders

We integrate multimodal neuroimaging with behavioral, clinical and digital phenotyping across cross-sectional and longitudinal study designs to identify neural circuit abnormalities underlying symptoms of brain disorders and inform personalized treatment strategies. Using machine learning, statistical inference, functional connectivity, signal processing, computational modelling and neuroinformatics, we develop quantitative methods and software tools to map neural dynamics to behavior, cognition and clinical symptoms and establish reproducible brain-behavior associations at the single-subject level.

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Our Work

Discover how our lab contributes to open and inclusive human brain research.

Research

Projects

Focusing on the analysis of functional neuroimaging data (e.g. resting-state fMRI, EEG) and behavioral/clinical data, we develop quantitative approaches to test hypotheses on the neurobiological mechanisms underlying specific symptoms and cognitive impairments in psychiatric disorders such as schizophrenia.

  • Longitudinal Imaging of Schizophrenia in Adults (LISA)
  • Neural dynamics modelling
  • Brain states in fMRI and EEG
  • Open-source BrainCAP software development
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Projects
Publications
Papers

Publications

Check out our recent peer-reviewed journal articles.

  • Lee et al. (Biological Psychiatry 2025)
  • Lee et al. (PLoS Biology 2024)
  • Lee et al. (Neuroimage 2022)
  • Lee et al. (Neuroimage:Clinical 2018)
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Development

Software

We develop open-source software tools to analyze neuroimaging and behavioral measurements to help scientists conduct research with greater efficiency, reproducibility, and transparency.

  • BrainCAP (under development): https://github.com/Kangjoo/BrainCAP/tree/develop
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Software

Latest News

See what's new in the CNBD laboratory.

Opportunities for BME Undergraduates

Opportunities for BME Undergraduates

Mar. 16, 2026

We welcome undergraduate BME/Neuroscience students to join our lab through the ARCH Program (Honors College) or the Coulter Undergraduate Research Excellence (CURE) Program for entry-level undergraduates.

Dr. Lee to Receive BBRF/NARSAD Young Investigator Grant

Dr. Lee to Receive BBRF/NARSAD Young Investigator Grant

July 30, 2026

Dr. Lee has been selected to receive the 2026 BBRF (formerly NARSAD) Young Investigator Grant, a highly competitive award supporting outstanding early-career investigators in brain and behavioral research. The grant will support Dr. Lee's research project from January 15, 2027, through January 14, 2029. Congratulations!

Cienna Shanklin — ARCH Program Student

Cienna Shanklin — ARCH Program Student

August 9, 2026

Cienna's proposal for the Honors College ARCH Program has been accepted to start in Fall 2026. Through the ARCH Program, Cienna has also officially joined the CNBD Lab. Congratulations!

Welcoming New BS student!

Welcoming New BS student!

September 1, 2026

We are excited to welcome our new undergraduate volunteer, Susanne Lopez (BS in Behavioral Neuroscience and Natural & Applied Sciences), to our team. Welcome Susanne!

Interested in working with us?

Join us based in the Department of Biomedical Engineering at Florida International University.

Email Dr. Lee BME PhD Program